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Discussion Using real-world data from 29,146 propensity score–matched veterans with T2D who initiated SGLT2i versus GLP-1RA treatment and met eligibility criteria, we reported that patients treated with SGLT2i had a 35% hazard reduction of developing the composite endpoint (≥40% decline in eGFR, ESKD event, or all-cause mortality), compared with matched veterans initiated with GLP-1RA
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Agents in this class are approved for treatment of type 2 diabetes and reduction of cardiovascular disease, as well as weight management
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