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In a study of semaglutide efficacy, the average reduction in weight from baseline was 10.2%, but 4.9% of patients achieved over 25% reduction from baseline, and 32.2% achieved less than a 5% reduction from baseline or even weight gain 5
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6,10 Paramedics should also be watchful for hypoglycemia, especially when combined with other drugs used to treat diabetes, as well as pancreatitis or biliary disease
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